Select Publications

Orgel KA, Duan S, Wright BL, Maleki SJ, Wolf JC, Vickery BP, Burks AW, Paulson JC, Kulis MD, Macauley MS. (2016) Exploiting CD22 on Antigen-Specific B-Cells to Prevent Allergy to the Major Peanut. Journal of Allergies and Clinical Immunology. 6749(16): 30799-0.

Link: https://www.ncbi.nlm.nih.gov/pubmed/27554819

Macauley MS, Kawasaki N, Peng W, Wang SH, He Y, Arlian BM, McBride R, Kannagi R, Khoo KH, Paulson JC. (2015) Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man. Journal of Biological Chemistry. 290(50): 30066-77.

Link: https://www.ncbi.nlm.nih.gov/pubmed/26507663

Angata T, Nycholat CM, Macauley MS. (2015) Therapeutic Targeting of Siglecs using Antibody- and Glycan-based Approaches. Trends in Pharmacological Sciences. 36(10): 645-60.

Link: https://www.ncbi.nlm.nih.gov/pubmed/26435210

Macauley MS and Paulson JC. (2014) Siglecs induce tolerance to cell surface antigens by BIM-dependent deletion of the antigen-reactive B cells. Journal of Immunology. 93(9): 4312-4321.

Link: https://www.ncbi.nlm.nih.gov/pubmed/25252961

Macauley MS, Crocker PR, Paulson JC. (2014) Siglec regulation of immune cell function in disease. Nature Reviews Immunology. 14(10):653-666.

Link: https://www.ncbi.nlm.nih.gov/pubmed/25234143

Macauley MS, Pfrengle F, Rademacher C, Nycholat CM, Gale AJ, von Drygalski A, Paulson JC. (2013) Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis. Journal of Clinical Investigation, 123(7): 3074-3083.

Link: https://www.ncbi.nlm.nih.gov/pubmed/23722906

Macauley MS, He Y, Gloster TM, Stubbs KA, Davies GJ, Vocadlo DJ. (2010) Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes. Chemistry&Biology, 17(9): 937-948.

Link: https://www.ncbi.nlm.nih.gov/pubmed/20851343

Macauley MS, Bubb A, Martinez-Fleites C, Davies GJ, Vocadlo DJ. (2008) Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance. Journal of Biological Chemistry. 283(50): 34687-34695.

Link: https://www.ncbi.nlm.nih.gov/pubmed/18842583

Macauley MS, Whitworth GE, Debowski A, Chin D, Vocadlo DJ. (2005) Human O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective, cell permeable, mechanism-inspired inhibitors. Journal of Biological Chemistry. 280(27): 35313-35322.

Link: https://www.ncbi.nlm.nih.gov/pubmed/15795231

Click Here for a list of all Dr. Macauley’s publications.