Using Chemical Approaches To Study How Gylcans Influence Our Immune Cells.
Welcome to the Macauley Lab
Our lab uses advanced chemical and biochemical approaches to study Siglecs with the primary motivating question being:
What are the glycans recognized by Siglecs?
Tackling challenging questions in immunology with chemistry by:
- Creating Multivalent, genetically encoded Siglec probes
- Discovering foundational biological roles for Siglecs and their glycan ligands
- Manipulating cellular glycans with chemical probes
Our Latest Publications
The MAcauley LAb
Department of Chemistry
University of Alberta
Through interdisciplinary research, the Macauley Lab aims to better understand how glycans modulate our immune cells and develop small molecule tools and inhibitors.
The ability of our immune system to actively recognize our own cells and tissues are critical because mechanisms that maintain immune homeostasis continue to be incompletely understood.
Join Our Lab
Please contact Dr. Macauley if interested in our laboratory.
We encourage diverse applicants to apply. Please provide a copy of your CV.