Folio – New research approach could unlock some mysteries about Alzheimer’s

Press Release

New research approach could unlock some mysteries about Alzheimer’s.

If successful, the approach could have implications beyond the debilitating disease.


A new research project using a unique approach may help unlock clues as to how Alzheimer’s arises and point to potential targets for developing therapeutics to treat the disease.

The project, led by University of Alberta chemists Matthew Macauley and John Klassen, will examine glycans (sugars) that interact with CD33, an important protein that is strongly implicated in Alzheimer’s disease. The primary goal is to develop a strategy for getting more precise information on the molecular identity of these sugars.

Territorial Acknowledgement

The University of Alberta, its buildings, labs, and research stations are primarily located on the traditional territory of Cree, Blackfoot, Métis, Nakota Sioux, Iroquois, Dene, and Ojibway/Saulteaux/Anishinaabe nations; lands that are now known as part of Treaties 6, 7, and 8 and homeland of the Métis. The University of Alberta respects the sovereignty, lands, histories, languages, knowledge systems, and cultures of First Nations, Métis and Inuit nations.

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