Select Publications
2021
Nguyen L$, McCord KA$, Bui TB, Bouwman KM, Kitova EN, Kumawat D, Daskhan GC, Tomris I, Han L, Chopra P, Yan TJ, Willow SD, Mason AL, Lowary TL, West LJ, Hsu STD, Tompkins SM, Boons GJ, de Vries RP, Macauley MS*, Klassen JS*. Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2. In Press at Nature Chemical Biology.
Jung J, Enterina JR, Bui DT, Mozaneh F, Lin PH, Nitin, Kuo CW, Rodrigues E, Bhattacherjee A, Raeisimakiani P, Daskhan GC, St. Laurent CD, Khoo KH, Mahal LK, Zandberg WF, Huang X, Klassen JS, Macauley MS. Carbohydrate sulfation as a mechanism for fine-tuning Siglec ligands. In Press at ACS Chemical Biology.
Bhattacherjee A, Daskhan GC, Bains A, Watson EAS, Eskandari-Sedighi G, St. Laurent CD, Voronova A, Macauley MS. (2021) Increasing phagocytosis of microglia through targeting CD33 with liposomes displaying glycan ligands. Journal of Controlled Release. 338:680-693.
Link: https://pubmed.ncbi.nlm.nih.gov/34517042/
Hong S, Yu C, Shi Y, Wang P, Chapla DG, Rodrigues E, Moremen KW, Paulson JC, Macauley MS, Wu P. (2021) Modulation of Siglec-7 Signaling via in situ Created High-Affinity cis Ligands. ACS Central Science. 7(8):1338-1346.
Link: https://pubmed.ncbi.nlm.nih.gov/34471678/
Sojitra M, Sarkar S, Maghera J, Rodrigues E, Carpenter E, Seth S, Ferrer Vinals D, Bennett N, Reddy R, Khalil A, Xue X, Bell M, Zheng RB, Zhang P, Nycholat C, Ling CC, Lowary TL, Paulson JC, Macauley MS, Derda R. (2021) Genetically Encoded, Multivalent Liquid Glycan Array (LiGA). Nature Chemical Biology. 17(7):806-816.
Link: https://pubmed.ncbi.nlm.nih.gov/33958792/
Link: https://pubmed.ncbi.nlm.nih.gov/33766097/
2020
Park H, Jaesoo J, Rodrigues E, Kitova E, Macauley MS, Klassen JS. (2020) Mass Spectrometry-based Shotgun Glycomics for Discovery of Natural Ligands of Glycan-binding Proteins. Analytical Chemistry. 92(20): 14012-14020.
Link: https://pubmed.ncbi.nlm.nih.gov/32936606/
Rodrigues E, Jung J, Park H, Loo C, Soukhtehzari S, Kitova EN, Mozaneh F, Daskhan G, Schmidt EN, Aghanya V, Sarkar S, Streith L, St. Laurent C, Nguyen L, Julien JP, West LJ, Williams KC, Klassen JS, and Macauley MS. (2020) A Versatile Soluble Siglec Scaffold for Sensitive and Quantitative Detection of Glycan Ligands. Nature Communications. 11(1):5091.
Link: https://pubmed.ncbi.nlm.nih.gov/33037195/
Movsisyan LD and Macauley MS. (2020) Structural Advances of Siglecs: Insight into Synthetic Glycan Ligands for Immunomodulation. Organic & Biomolecular Chemistry. 18(30):5784-5797.
Link: https://pubmed.ncbi.nlm.nih.gov/32756649/
Li Z, Kitov PI, Kitova EN, Mozenah F, Rodrigues E, Chapla DG, Moremen KW, Macauley MS, Klassen JS. CUPRA-ZYME: An assay for measuring carbohydrate-active enzyme activities, pathways and substrate specificities. Analytical Chemistry. 92(4):3228-3236.
Link: https://www.ncbi.nlm.nih.gov/pubmed/31961140
2019
Bhattacherjee A, Rodrigues E, Jung J, Luzentales-Simpson M, Enterina JR, Galleguillos D, St. Laurent CD, Nakhaei-Njad M, Fuchsberger FF, Streith L, Wang Q, Kawasaki N, Duan S, Bains A, Paulson JC, Rademacher C, Giuliani F, Sipione S, Macauley MS.Repression of Phagocytosis by Human CD33 is not Conserved with Mouse CD33. Communications Biology. 2, 450.
Link: https://pubmed.ncbi.nlm.nih.gov/31815204
Enterina J, Jung J, Macauley MS. (2019) Coordinated roles for glycans in regulating the inhibitory function of CD22 on B cells. Biomedical Journal. 42(2):218-232.
Link: https://www.ncbi.nlm.nih.gov/pubmed/31627864
Kitov PI, Kitova EN, Han L, Li Z, Jung J, Rodrigues R, Hunter CD, Cairo CW, Macauley MS, Klassen JS. (2019) A quantitative and high-throughput mass spectrometry-based glycan library screening method. Communications Biology. 2:268.
Link: https://www.ncbi.nlm.nih.gov/pubmed/31341967
Natoni A, Farrell ML, Harris S, Falanx C, Kirkham-Mccarthy, Macauley MS, Reagan MR, O’Dwyer M. (2019) Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model. Heamatologica. In Press.Link: https://www.ncbi.nlm.nih.gov/pubmed/31101754
Bednar KJ, Nycholat CM, Rao TS, Paulson JC, Fung-Leung WP, Macauley MS. (2019) Exploiting CD22 to Selectively Tolerize Autoantibody Producing B-cells in Rheumatoid Arthritis. ACS Chemical Biolology. 14(4):644-654.
Link: https://www.ncbi.nlm.nih.gov/pubmed/30835424
2018
Rodrigues E and Macauley MS. (2018) Hypersialylation in Cancer: Modulation of Inflammation and Therapeutic Opportunities. Cancers. 18;10(6).
Link: https://www.ncbi.nlm.nih.gov/pubmed/29912148
Briard JG, Jiang H, Moremen KW, Macauley MS*, Wu P*. (2018) Cell-based glycan arrays for probing glycan-glycan binding protein interactions. Nature Communications. 28;9(1):880. * co-corresponding authors
Link: https://www.ncbi.nlm.nih.gov/pubmed/29491407
Spiller F, Nycholat CM, Kikuchi C, Paulson JC and Macauley MS. (2018) Murine red blood cells lack ligands for B cell Siglecs, allowing strong activation by erythrocyte surface antigens. Journal of Immunology. 200(3):949-956.
Link: https://www.ncbi.nlm.nih.gov/pubmed/29288201
Bednar KJ, Shanina E, Ballet Ballet, Connors EP, Duan S, Juan J, Arlian BM, Kulis MD, Butcher EC, Fung-Leung WP, Rao TS, Paulson JC, and Macauley MS. (2017) Human CD22 Inhibits Murine B-cell Receptor Activation in a Human CD22 Transgenic Mouse Model. Journal of Immunology. 199(9): 3116-3128.
Link: https://www.ncbi.nlm.nih.gov/pubmed/28972089
2017
Orgel KA, Duan S, Wright BL, Maleki SJ, Wolf JC, Vickery BP, Burks AW, Paulson JC, Kulis MD, Macauley MS. (2017) Exploiting CD22 on Antigen-Specific B-Cells to Prevent Allergy to the Major Peanut. Journal of Allergies and Clinical Immunology. 6749(16): 30799-0.
Link: https://www.ncbi.nlm.nih.gov/pubmed/27554819
Lopez Aguilar A, Briard JG, Yang L, Ovryn B, Macauley MS, Wu P (2017) Tools for Studying Glycans: Recent Advances in Chemoenzymatic Glycan Labeling. ACS Chemical Biology. 12(3):611-621Link: https://www.ncbi.nlm.nih.gov/pubmed/28301937
